We are using high-resolution FE computational models to analyse mechanical properties and fracture behavior of human bone tissues. The structural geometries, i.e. meshes, are directly obtained from high-resolution synchrotron X-ray images.
The overall aim of the project is to improve synthesis and processing of ceramic-based bone cements, to achieve high-strength cements, possibly composites, adequate for use in load-bearing applications. This will permit a substitution of the less biocompatible acrylic-based cements in the clinics and/or a decreased number of painful and costly reoperations, associated to the low mechanical properties of today’s ceramic cements.
Specifically, we aim to:
• Develop a stronger base ceramic cement
• Develop mechanical models of fluid and solid polymer-reinforced ceramic cements
• Develop a ceramic-polymer composite, intended for biomedical applications
• Develop a delivery technique for the new cements
• Evaluate the novel cements in existing and novel applications at a bench-test level, namely through injection into bone as well as in the development of patient-specific skull implants