Gene expression in Behcets disease

Dnr:

SNIC 2016/7-57

Type:

SNAC Small

Principal Investigator:

Kaisa Thorell

Affiliation:

Karolinska Institutet

Start Date:

2016-05-31

End Date:

2017-12-01

Primary Classification:

30108: Cell- och molekylärbiologi

Webpage:

Allocation

Abstract

Behçet syndrome is a systemic inflammatory condition characterized by muco-cutaneous and ocular manifestations, with central nervous system, vascular and/or gastro-intestinal involvement. The association of microbiota with Behçet syndrome has not been shown yet. Our work is aimed to compare gene expression profiles of both human and microbial RNA in intestinal biopsies from Behçet syndrome patients and healthy control relatives.