Metagenomics and population genetics of nematode communities

Dnr:

SNIC 2017/7-96

Type:

SNAC Small

Principal Investigator:

Peter Halvarsson

Affiliation:

Sveriges lantbruksuniversitet

Start Date:

2017-06-02

End Date:

2018-07-01

Primary Classification:

40301: Medicinsk biovetenskap

Webpage:

Allocation

Abstract

The objective of this study is to develop and validate a NGS based protocol for species delineation of nematode communities that are present in complex samples composed of multiple species contained in different genera. Such a diagnostic tool is an essential prerequisite to investigate the dynamic alterations in parasite community structure relative to deworming strategies. The same technique can also be applied to study possible alterations in the nematode community structure in areas with differing levels of interaction between domestic livestock and wildlife ruminants, but also in relation to animal trade resulting in animal movement between regions and different farms. Accordingly we expect to get access to a tool so that we in detail can investigate the complex interplay between different host animals and their parasites, how this is influenced by various biological and environmental factors and colonization routes how resistance to antihemlintic drugs has spread among different farms.