CryoEM data is now being collected for several projects at the new national resource at SciLIfeLab. Processing of these data sets will require high speed computing. We have now 4 subprojects that have been alloted time at SciLifeLab. For all of these we have medium resolution data that shows that there is a clear potential to proceed to high resolution. Thus data collection will be done under optimum conditions. Moreover, the projects will require collection of very large data sets to overcome variability caused by heterogeneity of specimens. In addition to data collected at SciLifeLab we also have additional data sets obtained at other core infrastructure centers, that will be subjected to processing.