SNIC
SUPR
SNIC SUPR
Improving CRISPR/Cas9 screening methodologies
Dnr:

SNIC 2017/7-265

Type:

SNAC Small

Principal Investigator:

Bernhard Schmierer

Affiliation:

Karolinska Institutet

Start Date:

2017-12-01

End Date:

2019-12-01

Primary Classification:

30108: Cell and Molecular Biology

Allocation

Abstract

This project will be used to analyse our CRISPR/Cas9 screening data with the aim to set up and optimise alternative CRISPR screening methodologies such as CRISPRi, CRISPRa and CRISPR-X and improve the precision and applicability of these methods. Keywords: CRISPR; CRISPR/Cas9; genetic screening; lentiviral; pooled screening; high-throughput functional genomics