SNIC
SUPR
SNIC SUPR
Horizontal gene transfer between A. kona and bacteria
Dnr:

SNIC 2018/8-110

Type:

SNAC Small

Principal Investigator:

Sanea Sheikh

Affiliation:

Uppsala universitet

Start Date:

2018-03-08

End Date:

2019-04-01

Primary Classification:

10615: Evolutionary Biology

Webpage:

Allocation

Abstract

Acrasids (Heterolobosea, Excavata) are soil amoebae that undergo aggregative multicellularity when food becomes scarce to form small elevated sorocarps on the soil surface. Acrasids represent independent evolution of aggregative multicellularity and the only example of multicellularity in Excavata. This makes Acrasis a unique model system to study aspects of multicellularity such as cell-cell communication, differentiation and kin recognition. Around 10,881 A. kona genes are uniquely shared with various groups of non-excavate organisms, suggesting recent acquisition by horizontal transfer. This includes genes apparently acquired from bacteria and expanded into multigene families in A. kona, some of which appear to be targeted to the cell membrane. This project aims to study those genes in detail.