SNIC
SUPR
SNIC SUPR
Identification of coactivetor of transcription factor Fra-1
Dnr:

SNIC 2018/8-216

Type:

SNAC Small

Principal Investigator:

Indranil Sinha

Affiliation:

Karolinska Institutet

Start Date:

2018-06-13

End Date:

2019-07-01

Primary Classification:

10610: Bioinformatics and Systems Biology (methods development to be 10203)

Webpage:

Allocation

Abstract

Fra-1, a member of the activator protein 1 (AP-1) family, is overexpressed in triple-negative breast cancer (TNBC) and plays crucial roles in tumor progression. We have identified few proteins interacting with endogenous chromatin-bound Fra-1 in triple negative breast cancer cells. By combining RNA-seq and ChIP-seq approaches we aim to study few coactivetor of Fra-1.