SNIC
SUPR
SNIC SUPR
ATAC-seq S2 cells
Dnr:

SNIC 2018/8-294

Type:

SNAC Small

Principal Investigator:

Neus Visa

Affiliation:

Stockholms universitet

Start Date:

2018-09-28

End Date:

2019-11-01

Primary Classification:

10602: Biochemistry and Molecular Biology

Allocation

Abstract

We are interested in understanding the role of chromatin-associated RNA (caRNA) in the regulation of chromatin compaction. We have already carried out RNAi experiments to deplete exosome subunits in S2 cells (Drosophila melanogaster) and we carried out RNA-seq experiments to detect caRNAs that are exosome-sensitive. We are now carrying out ATAC-seq to correlate RNA levels with chromatin compaction genome-wide.